Chemistry

Chemistry

Department Chair: Henry Jakubowski 

Faculty: George Anquandah, Md Abul Fazal, Kate Graham, Rachel Hutcheson, John Hoody, Henry Jakubowski, Brian Johnson, T. Nicholas Jones, Edward McIntee, Anna McKenna, Alicia Peterson, Michael Ross, Chris Schaller, Carleen Schomer OSB, Christen Strollo Gordon Richard White

A degree in chemistry, in addition to being an excellent preparation for industrial employment, graduate study or secondary teaching, also prepares students to apply for further study in the areas of medicine, law, business administration, government service and agriculture science. To this end, the department offers a variety of introductory and advanced courses.

CHEM 125 is intended as an introductory chemistry course for all natural science majors.  It provides students with a comprehensive survey of chemical structure and ensuing chemical and physical properties that arise from structure.  CHEM 125, together with the separate lab course, CHEM 201, fulfills the Common Curriculum Natural Science requirement.  200-300 level courses are intended for the students seeking a major degree in chemistry or biochemistry, and a minor degree in chemistry; they also serve as supporting courses for students majoring in biology, natural science, or nutrition science, and for pre-health profession students.

Starting in Spring 2014, students majoring in nutrition with a dietetics concentration will take CHEM 250.

The Chemistry Department is in the midst of a major change in its curriculum that will result in changes in the required courses for science majors taking courses past CHEM 125. These changes will continue through Spring 2014. First year students enrolling in Fall 2011 will be the first to complete the full four years of the new curriculum.

The new curriculum consists of one introductory course (4 credits), five foundation courses (4 credits each), four separate foundation lab courses (0 or 1 credits each), one in-depth Integrated Lab course (4 credits each), and a series of half-semester in-depth courses (2 credits each).  In Fall 2013 and Spring 2014, Juniors (who enrolled in 2011) will take 2 credit in-depth courses while Seniors (who enrolled in 2010) will take four credit in-depth courses from our old curriculum.  In some cases, where possible and with the permission of the Department Chair, Seniors may be allowed to substitute two of the new in-depth courses for one, four credit course.

The overall structure of our new curriculum has been approved by the CSB/SJU Curriculum Committee.  Please consult the latest electronic versions of the course catalog for the most recent approved courses.

Assessment

Each year, the Chemistry Department assesses its overall program and its students in a number of ways. For example, several courses employ standardized final exams for which there are national norms. All chemistry majors are required to take a nationally-normed exam (CHEM XXX) in the spring of their senior year. In addition, senior majors are asked to complete an anonymous survey to probe the extent to which they believe the department meets its stated goals and objectives. Every 5-7 years, the department must be re-accredited by the American Chemical Society, and, at similar intervals, departmental alumni are polled to obtain their evaluation of the education they received in the department. All of this information is employed to improve our program and ensure that the educational opportunities we provide are the best possible. Based on our assessment program and new Common Curriculum requirements, we will continue to make changes in courses and requirements that will promote student learning.

Major

The Chemistry Department offers a single major in Chemistry with options for different concentrations and ACS certification.

  • For students enrolled before Fall 2011, students may choose either an American Chemical Society (ACS)-certified concentration or a traditional concentration;
  • For students enrolled in Fall 2011 and after, students can major in Chemistry without a specific concentration (any 3 half-semester in-depth courses required) or they can choose to take a concentration in Chemical Biology, Environmental Chemistry, or Industrial/Materials Chemistry (4 in-depth courses from specific list required).  Students with or without a concentration will be certified by the ACS if they take a total of six half-semester in-depth courses. 

In addition, an interdisciplinary biochemistry major is available (see Biochemistry major page).

In either our old or new curriculum, students who intend to pursue graduate work in chemistry and related fields, or those seeking immediate employment in chemical industry or government laboratories, should take sufficient courses to be certified by the ACS.  Students enrolling in Fall 2011 and later, can, in addition, choose either a specific concentration (Chemical Biology, Environmental Chemistry, or Industrial/Materials Chemistry) that would prepare them for a study in graduate school or for a particular industry.  They could also choose no concentration but still be ACS-certified which will prepare them well for graduate school or industry. 

Students who have an interest in chemistry, but are not necessarily planning to continue their study of chemistry at the graduate level, could major in chemistry with a traditional concentration (students enrolled before Fall 2011) or with (four in-depth courses) or without a concentration (three in-depth courses) but without ACS certification (students enrolled in Fall 2011 and later). This option is recommended for those planning careers in any of the medical fields, secondary education, patent law, government service, environmental science, as well as management-level positions in the chemical industry. 

Concentrations, but not ACS certification, will appear on a student's transcript.

For students enrolled before Fall 2011 (old curriculum): 

ACS Concentration (62 credits)
Required Courses:
CHEM 125 (taught in Fall 2010 with an attached lab), 234, 235, 236, 333, 334, 335, 336, 341, 349 and BCHM 322, plus either two credits or CHEM 360 or CHEM 398; PHYS 105, 106 or PHYS 191, 200; MATH 119, 120.  The Chemistry Comprehensive Exam (CHEM XXX) is also required. (Note: The ACS recommends either MATH 124 or 239, but they are no longer required.)

Traditional Concentration (50 credits)
Required Courses:
CHEM 125 (taught in Fall 2010 with an attached lab), 234, 235, 236, 333 or 334, 335, 349, two additional courses selected from 333, 334, 336, 341, and BCHM 322, plus either two credits CHEM 360 or CHEM 398; MATH 119, 120; PHYS 105, 106 or PHYS 191, 200. The Chemistry Comprehensive Exam (CHEM XXX) is also required.

Special Requirements For All Concentrations:
Senior majors are required to give a seminar presentation on their laboratory or library research (CHEM 360 or 398) and to take a comprehensive exam in chemistry (CHEM XXX).

For students enrolled Fall 2011 and after (new curriculum):

All majors must take the following chemistry courses:

  • Introductory Course:  CHEM 125;
  • Foundation 4 Credit Courses:  CHEM 250, 251, 252, 255 (all approved) and 318 (pending approval, Sp 2013);
  • Foundation 0 or 1 Credit Lab Courses:  CHEM 201, 202, 203, and 205 (all approved);
  • In-depth Integrated Lab Course:  CHEM 305
  • CHEM 349, CHEM 360 or CHEM 398, CHEM XXX.

In addition, all majors must take the following support courses:

  • MATH 119, MATH 120; (MATH 124 or 239 recommended)
  • PHYS 105 or 191; PHYS 106 or 200.

Majors must take the following 3oo level 2 credit in-depth courses (numbered CHEM 3XX if the course is pending approval) depending on their choice of concentration and ACS Certification. 

No Concentration AND no ACS certification: Any 3 In-depth courses (CHEM 3XX,)

Chemical Biology Concentration AND no ACS certification: Chemical Biology (CHEM 347);  Three additional 2 credit in-depth classes taken from the following:  355 (Analysis of Biomolecules), 353 (Xeniobiotic Metabolism), 348A (Molecular Design), the following CHEM 3XX courses pending approval: Biomacromolecules, Signal Transduction and Neural Chemistry, and Medicinal Cheminstry, and specified topic courses approved for the concentration (321-326);  BIOL 318: Molecular Genetics  OR appropriate courses from other departments approved by the Chemistry Department may substitute for two credit in-depth course(s).  BIOL 121 and BIOL 221 are highly recommended for majors

Environmental Chemistry AND no ACS certification: Climate and Habitat Change (CHEM 343); Three additional 2 credit in-depth classes taken from the following: 353 (Xeniobiotic Metabolism),  the following CHEM 3XX courses pending approval: Environmental Chemistry A: Atmosphere, Environmental Chemistry B: Soil and Water , Sustainable Energy, Separation Science, Insight into Mechanisms, Structure Elucidation, and specified topic courses approved for the concentration (321-326); Appropriate courses from other departments approved by the Chemistry Department may substitute for CHEM 3XX course(s).

Materials/Industrial Chemistry AND no ACS certification:  Industrial and Engineering Processes (CHEM 345) and Nanomaterials (CHEM 346); Two additional 2 credit in-depth classes taken from the following: 343 (Climate Change), 355 (Analysis of Biomaterials), 348A (Molecular Design), the following CHEM 3XX course pending approval: Separation Science, and specified topic courses approved for the concentratin (321-326).  Appropriate courses from other departments approved by the Chemistry Department may substitute for CHEM 3XX course(s).

ACS Certification:

Students taking any of the options above (no concentration or any of the concentration) can be certified by the ACS if they take a total of six, 2 credit in-depth courses. 

Total Number of Credits for the Chemistry Major (including support courses):

No Concentration: 52-57 without ACS Certification; 60-65 with ACS Certification

Chemical Biology, Environmental Chemistry, or Materials/Industrial Chemistry Concentrations: 56-61 credits w/o ACS; 60-65 with ACS Certification

Minor (24-28 credits)

The minor is recommended for those students whose major interests are in other academic areas, which can be strengthened by a concentration in chemistry.

Required Courses:

For students enrolled before Fall 2011: CHEM 125 (taught in Fall 2010 with an attached lab), 234, 235, 236, 335 and one of the following courses: 333, 334, 336, 341, or BCHEM 322.


For students enrolled in Fall 2011 and later: CHEM 125, 250, 251, 255, 315 and CHEM 318 (pending approval); CHEM 201, 202, 203 and 205 (0 or 1 credit labs).

Courses (CHEM)

105 Chemistry and Society. (4)
Fundamentals of chemistry are studied with the aim of gaining an understanding of the importance of chemistry for humanity and society. Topics of historical interest and current relevance are explored. Laboratory emphasis is on the principles of scientific inquiry, including the collection, analysis and interpretation of data. Intended primarily for non-science majors. Fall and spring.

115 Introductory Chemistry Topics 1. ( (0 or 1)
First year students intending to become Chemistry or Biochemistry majors will form a cohesive and supportive peer group as they are introduced to modern chemistry research and opportunities and develop practical and leadership skills. This course will be required of all students participating in the FoCuS program. The instructor for this course will serve as their advisor. Topics will include applying for summer research positions, studying for chemistry exams, an introduction to scientific literature, developing resilience s they face challenges in becoming independent learners, and balancing leadership, service and academic commitments. Prerequisite or Corequisite: 125. Fall.

116 Introductory Chemistry Topics 2.  (0 or 1)
A continuation of Introductory Chemistry Topics 1. This course will be required of all students participating in the FoCuS program. The instructor for this course will serve as their advisor. Topics will include applying for summer research positions, studying for chemistry exams, an introduction to scientific literature, developing resilience as they face challenges in becoming independent learners, and balancing leadership, service and academic commitments. Prerequisite: 115. Spring.

121 Skills in Chemistry. (2)
This course will help students develop the visualization, problem solving, and critical thinking skills necessary for success in CHEM 125. Students will work in small groups in a student-centered learning environment that will provide support as they address some of the challenging concepts in chemical structure and properties. The course content will be coordinated closely with the first half of CHEM 125 and will be scheduled to run parallel to it. The course is intended for students who have been identified as likely benefiting from this experience.  Must also register for CHEM 125.

125 Introduction to Chemical Structure and Properties. (4)
And introductory chemistry course in which students study how the structure of atoms, ions, and molecules determine their physical and chemical properties.  Starting with atoms and their electron configurations, students build a progressive and linked understanding of bonding, ionic and molecular geometry, and physical and chemical properties that emerge from structure.  Intended as a first course for students majoring in the natural sciences.  Prerequisite: ACT Math Score 24, SAT Math Score 575 or concurrent enrollment in CHEM 121.

201  Purification and Separation Lab 1. (0,1).
An introductory laboratory course in basic purification techniques and analysis in chemistry.  Emphasis is on mastery of technique and analysis of experimental data  Students usually co-enroll in CHEM 125 and 201. However, students may withdraw from either one during the semester and take that course in a subsequent semester. Students who take CHEM 121 and CHEM 125 in the same semester should take CHEM 201 lab in the following semester.
Students must complete both CHEM 125 and CHEM 201 in order to earn the NS designation.
If a student only completes CHEM 125 they will not earn the NS designation for the Common Curriculum.
If a student only completes CHEM 201 they will not earn the NS designation for the Common Curriculum.

202 Purification and Chromatography Lab 2. (0 or 1)
A laboratory course in the use of chromatography as a tool to purify and analyze chemistry mixtures. Emphasis is on mastery of techniques and analysis of experimental data. Prerequisite: CHEM 201.
If a student only completes CHEM 125 they will not earn the NS designation for the Common Curriculum.
If a student only completes CHEM 201 they will not earn the NS designation for the Common Curriculum.

203 Synthesis Lab. (0 or 1)
A laboratory course in synthetic techniques. Students will learn a variety of techniques for synthesis including air sensitive, biochemical and organic reactions. Students will continue to develop independence, literature searching, project design, data interpretation and writing skills. Prerequisites: CHEM 202 and 250 or department permission. A-F grading only.

205 Measurement Lab. (0 or 1)
A laboratory introduction to the science of chemical measurement. Using classical techniques (quantitative analysis, spectroscopic techniques) students will learn to measure important physical and chemical properties, quantitate and minimize measurement errors, and obtain accurate calibrations. Laboratory experiments will focus on student development of precision and accuracy, data analysis and reporting as well as scientific writing. Prerequisite: CHEM 201. A-F grading only.

215 Problem Solving Seminar. (1)
This is the first course in a year-long sequence and is required for all students participating in the NSF sponsored FoCuS program in their sophomore year. This course is open to other students with instructor approval only. In this course students will work on small research problems in groups. The instructor will serve as their coordinator. The goal of this course is to expose the students to a sampling of fundamental and applied research problems, develop problem solving and communications (written and oral) skills and prepare them for advanced laboratory research projects. Resources and methods for searching the chemical literature, proper referencing protocols, and technology enhanced presentation skills will be emphasized. The assigned problems will engage students in hands-on activities and provide a supportive environment to develop their confidence in understanding, operating and manipulating isntruments and computational methods. At the end of the semester students will present their results through written reports and oral presentations. Prerequisite: CHEM 125, CHEM 250, CHEM 201, CHEM 202.

216 Problem Solving Seminar II (1)
This is the second course in a year-long sequence and is required for all students participating in the NSF sponsored FoCuS program in their sophomore year. This course is open to other students with instructor approval only.  The course description parallels that of CHEM 215. Prerequisite: CHEM 125, CHEM 250, CHEM 201, CHEM 202, CHEM 215.

250 Reactions of Nucleophiles and Electrophiles (Reactivity 1). (4)
An understanding of chemical reactivity is developed based on principles of Lewis acidity and basicity. The formation, stability and reactivity of coordination complexes serves as an introduction to electrophilicity, nucleophilicity, and steric and electronic effects. Investigations of carbonyl reactivity (addition and substitution) using analogous principles are used to develop pattern recognition skills in understanding chemical processes. Some emphasis is placed on energetics as a basis of understanding reactivity. Together, these topics lead to an understanding of simple biochemical pathways. Applications of the material are drawn from organic, biological and inorganic chemistry. Prerequisite: CHEM 125.

251 Intermediate Reactions of Nucleophiles and Electrophiles (Reactivity 2). (4)
An understanding of chemical reactivity, initiated in Reactivity 1, is further developed based on principles of Lewis acidity and basicity. Alternative mechanisms of ligand substitution in coordination complexes are considered in terms of steric and electronic effects. An understanding of kinetic evidence is developed in order to determine which mechanism has occurred in a particular case. Organic nucleophilic substitution pathways are studied using analgous principles. Electrophilic addition and substitution in pi systems (alkenes and aromatics) are used to extend these principles to new systems and complete an overview of polar reactions. Applications of the material are drawn from organic, biological and inorganic chemistry. Prerequisite: CHEM 250.

255 Macroscopic Chemical Analysis (4)
Use of statistical and thermodynamic approaches to develop understanding of analytical and physical techniques and theory. Emphasis on free energy as the driving force for chemical reactions will be explored through the study of chemical equilibriums in simple and complex systems. Statistical methods will be developed for the assessment of data and prediction of system change. The laws of thermodynamics will be applied to chemical systems in equilibrium as well as in dynamic situations. Prerequisite: CHEM 125.

271 Individual Learning Project. (1-4)
Supervised reading or research at the lower-division level. Permission of department chair required. Consult department for applicability towards major requirements. Not available to first-year students.

305 Integrated lab (4) 
Students will conduct multiple cross-discipline and open-ended projects that will include components of experimental design, method development, synthesis, separation, instrumental analysis, molecular modeling, quantitative data analysis and written/oral presentations of lab results and discussions.  This lab replaces all those previously attached to Junior and Senior level upper division courses in our old curriculum.  Prerequisites:  CHEM 201, 202, 203, and 205;  Corequisite: CHEM 315, 318.

315 Advanced Reactions (Reactivity 3). (4)
An understanding of chemical reactivity, developed in Reactivity 1 and 2, is extended to non-polar systems through the study of redox, radical, photochemical and pericyclic reactions.  Molecular orbital theory is exploited to explain a number of reactions. With a firm understanding of an array of reactions in hand, a number of applications, including biochemical pathways such as oxidative phosphorylation and photosynthesis, are examined in detail. The roles of enzyme catalysis, enzyme cofactors and regulatory pathways are also explored. Prerequisite: CHEM 251.

318 Microscopic Chemical Analysis. (4)
Exploration of chemical systems from a quantum mechanical perspective. Spectroscopy will be emphasized as one of the techniques that link theory with data. Statistical methods will be developed for the assessment of instrumentation as well as a fundamental understanding of spectroscopic and chromatographic techniques used in the analysis and exploration of chemical properties. Prerequisite: CHEM 255; Prerequisite or Corequisite: MATH 120; PHYS 106 or 200.

321-326 Topics in Chemistry. (1-4)
The Chemistry Department offers a series of topics courses, 321-326. These courses, offered for variable credit, cover the major areas in chemistry and are used to extend or supplement topics introduced in previous chemistry courses.
 321 Topics in Computational Chemistry. (1-4)
 322 Topics in Analytical Chemistry. (1-4)
 323 Topics in Biochemistry. (1-4)
 324 Topics in Inorganic Chemistry. (1-4)
 325 Topics in Organic Chemistry. (1-4)
 326 Topics in Physical Chemistry. (1-4)

333 Chemical Thermodynamics and Kinetics. (4)
Topics include the principles of thermodynamics applied to chemical systems, kinetic molecular theory, and chemical kinetics. Laboratory emphasis is on chemical thermodynamics and kinetics, and computer refinement of data. Prerequisites: 236, 8 credits of physics, MATH 120. Fall.  This course will not be offered after Fall 2013.

334 Quantum Chemistry and Structure of Matter. (4)
Topics include quantum theory of atomic and molecular systems, atomic and molecular spectroscopy and statistical thermodynamics. Laboratory emphasis is on computational quantum chemistry and analysis of spectroscopic data. Prerequisites: 236, 8 credits in physics, MATH 120. Spring. This course will not be offered after Spring 2013.

335 Analytical Chemistry. (4)
A study of the theories and techniques of modern analytical chemistry. Emphasis is on the kinds of chemical problems that can be explored using quantitative methods of analysis. Problem solving and quantitative reasoning skills are used to: 1) design appropriate experiments, 2) acquire and analyze data and 3) assess errors. The laboratory focuses on the separation and analysis of multi-component systems. Prerequisite: 234. Fall.  This course will not be offered after Fall 2013.

336 Advanced Analytical Chemistry. (4)
Modern theory and techniques with emphasis on instrumentation. Topics include electrolysis, pulse polarography, spectrophotometry, flame techniques and chromatography. Laboratory emphasis is on polarographic methods, advanced spectrophotometric techniques, HPLC and GC, atomic absorption and computer interfacing to instruments. Prerequisites: 335, PHYS 105 or 191. Spring. This course will not be offered after Spring 2014.

341 Advanced Inorganic Chemistry. (4)
Topics include periodicity, advanced bonding theories (particularly as applied to inorganic systems), main group elements, solid state chemistry, coordination compounds, organometallic compounds and catalysis. Laboratory emphasis is on the synthesis, characterization and reactivity of inorganic compounds. Prerequisite: 333 or 334. Spring. This course will not be offered after Spring 2014.

343 Climate & Habitat Change. (2)
Along with the positive advances that result from chemistry, copious amounts of toxic and corrosive chemicals have also been produced and dispersed into the environment. The course will address selections from different areas of environmental study that impact our climate and habitat. Specific topics could include; global warming, ozone depletion, pollution, energy production and usage, and toxic waste disposal. Approaches for remediation will be discussed. Prerequisites: CHEM 250 and 255.

345 Indust Engineering Processes. (2)
This course is intended to teach students the underlying principles in the operation and process development of a product for industrial scale mass production. Topics for this course will include; testing/trials, production design, and resource management. Prerequisite: CHEM 255.

346 Namomaterials. (2)
This course will focus on the fundamental principles in nanomaterials. Topics may include; structural materials, conductors, semiconductors, sensors, or polymers. The students will be presented with current synthetic techniques for the production of bulk and nanostructured materials along with analytical methodologies to physically characterize materials. Prerequisites: CHEM 315 or 318 NOTE: The in-depth courses do not require a completion of all the foundation courses indicated by the specified prerequisite course(s).

347 Chemical Biology. (2)
Chemical biology will cover topics of current interest in chemical biology and will survey the way in which small molecules are used to investigate and manipulate biological systems wither for a biological or chemical purpose. Specific topics may include; protein design, development of unnatural biological molecules, peptide-carbohydrate interactions, combinatorial synthesis/libraries, molecular recognition, chemical genetics, biosynthesis, and methods of drug discovery. Prerequisite: CHEM 251 Recommended: BIOL 121 and CHEM 315.

348 Molecular Design. (2)
Molecular design and catalysts are important applications of chemical reactivity concepts. In this course, students will learn about some current methods useful in synthesis and see these methods applied in the synthesis of complex molecules. Topics may include; organo-transition metal reactions, catalytic methods of enantioselective synthesis and retrosynthetic analysis. Students will demonstrate basic proficiency in these areas and also carry out detailed analyses of total syntheses from the current literature. Pre- OR co-requisite CHEM 315.

349 Chemistry in Experience and Practice. (0-1)
Students in their junior and senior years will participate in and write reflections about structured activities designed to explore jobs, graduate education, research, and general career options in chemistry. Students must enroll in Fall of their junior year. Students will receive a grade in their senior year. Required for Chemistry majors.

350 Library Research Seminar. (1-2)
In-depth library research and reading primary sources on a single topic; emphasis of seminar is on comprehension and criticism. 

351 Lab Research Seminar. (1-4)
Independent laboratory research experience with emphasis on modern techniques and equipment. Seminar. Prerequisite: 320.

353 Xenobiotic Metabolism. (2)
This course will explore biological mechanisms of activation and detoxification of xenobiotics. Topics will include; oxidation/reduction mechanisms (e.g. Cytochrome P450, Flavin Mono-Oxygenase), transferase reactions (e.g. Glutathione S-Transferase, Glycosyltransferases, Acetyltransferases), adduct formation, and repair mechanisms. Prerequisite: CHEM 315 Recommended: BIOL 121.

355 Analysis of Biomaterials. (2)
This course provides an overview of principles of bioanalytic methods and the application of modern instrumental techniques to biological systems. Particular focus will be placed on fundamental principles and analytical measurements of biomolecules, immunoassays, separations, biological mass spectrometry, microscopy, and imaging. Emerging technologies such as nanotechnology-enabled biosensors, microfluidic devices, and lab-on-chip may also be addressed. Error analysis, statistical treatment of data, and validation of bioanalytical methods and devices are included. Prerequisite: CHEM 255 and 205 Recommended: BIOL 121.

359 Symmetry & Spectroscopy. (2)
Symmetry, group theory, and molecular orbital theory will be used to explore and explain the behavior of chemical systems on the molecular and atomic scale. The emphasis will be to develop orbital theory in order to gain an understanding of observed spectroscopic behavior such as Raman, IR, and UV. Additionally, symmetry and orbital theory will be used to explain chemical reactivity using models such as Woodward-Hoffman rules and photochemical selection rules. Prerequisite: CHEM 318.

360 Senior Capstone Research. (2-4)
Capstone library research (2) or laboratory research (2-4) done under the supervision of a faculty advisor. Students receiving ACS certification or selecting a concentration in Chemical Biology, Environmental Chemistry of Materials/Industrial Chemistry require 4 credits of CHEM 360.  Required for all chemistry majors except those completing HONR 398 (Honors Senior Research) which fulfills the research and capstone requirement.  Students also attend regular class meetings focusing on their research progress, literature review, and preparation of a final paper and oral presentation given at the end of their senior year. Although students may register for the course in the Fall and/or Spring semesters of their senior year, the must select an advisor and sign a research contract in the beginning of their senior year.  A grade is given after the final presentation and paper. Satisfies the Experiential Learning requirement of the Common Curriculum.

371 Individual Learning Project. (1-4)
Supervised reading or research at the upper-division level. Permission of department chair and completion and/or concurrent registration of 12 credits within the department required. Consult department for applicability towards major requirements. Not available to first-year students.

397 Internship. (4-16)
Completed Application for Internship Form REQUIRED See Internship Office Web Page.

398 Honors Senior Essay, Research or Creative Project. (4)
Required for graduation with "Distinction in Chemistry." Prerequisite: HONR 396 and approval of the department chair and director of the Honors Thesis program. For further information see HONR 398.

XXX Chemistry Comprehensive Exam. (0)
Required for graduation with a chemistry or biochemistry major. Spring.

Two credit, half-semester classes offered starting Fall 2013:

Course descriptions for a series of 2 credit in-depth classes are given below.  In-depth courses do not require completion of all the foundation courses as indicated by the specified prerequisite course(s).    

CHEM 355: Analysis of Biomaterials (offered in even years) 
This course provides an overview of the physico-chemical principles of bioanalytic methods and the application of modern instrumental techniques to biological systems. Particular focus will be placed on fundamental principles and analytical measurements of biomolecules, immunoassays, separations, biological mass spectrometry, microscopy and imaging. Emerging technologies such as nanotechnology-enabled biosensors, microfluidic devices and lab-on-chip will also be addressed. Error analysis, statistical treatment of data and validation of bioanalytical methods and devices are included. Prerequisite:  CHEM 255 or CHEM 205

CHEM 343: Climate and Habitat Change (offered every year and required for a concengration in Environmental Chemistry)
Along with the positive advances that result from chemistry, copious amounts of toxic and corrosive chemicals have also been produced and dispersed into the environment.  The course will address selections from different areas of environmental study that impact our climate and habitat.  Specific topics could include global warming, ozone depletion, pollution, energy production and usage and toxic waste disposal.  Approaches for remediation will be discussed.  Prerequisites: Chem 250 & 255

CHEM 345: Industrial and Engineering Processes(offered every year and required for a concentration in Industrial/Materials Chemistry)
This course is intended to teach students the underlying principles in the operation and process development of a product for industrial scale mass production.  Topics for this course will include testing/trials, production design, and resource management. Prerequisite:  CHEM 255. Note:  The in-depth courses do not require completion of all the foundation courses as indicated by the specified prerequisite courses

CHEM 346A: Nanomaterials (offered in even years and required for a concengration in Industrial/Materials Chemistry)
This course will focus on the fundamental principles in nanomaterials.  Topics may include structural materials, conductors, semiconductors, sensors or polymers.  The students will be presented with current synthetic techniques for the production of bulk and nanostructured materials along with analytical methodologies to physically characterize materials. Prerequisites: CHEM 315 OR 318 

CHEM 347: Chemical Biology (offered every year and required for a concetration in Chemical Biology) 
Chemical biology will cover topics of current interest in chemical biology and will survey the way in which small molecules are used to investigate and manipulate biological systems either for a biological or chemical purpose. Specific topics may include protein design, development of unnatural biological molecules, peptide-carbohydrate interactions, combinatorial synthesis/libraries, molecular recognition, chemical genetics, biosynthesis and methods of drug discovery. Prerequisite: CHEM 251 Recommended: BIOL 121 and CHEM 315 

CHEM 348AMolecular Design (offered in even years)
Molecular design and catalysis are important applications of chemical reactivity concepts.  In this course, students will learn about some current methods useful in synthesis and see these methods applied in the synthesis of complex molecules. Topics may include organo-transition metal reactions, catalytic methods of enantioselective synthesis and retrosynthetic analysis.  Students will demonstrate basic proficiency in these areas and also carry out detailed analyses of total syntheses from the current literature. Pre- OR Co-requisite: CHEM 315

CHEM 353: Xenobiotic Metabolism (offered in even years)
This course will explore biological mechanisms of activation and detoxification of xenobiotics. Topics will include oxidation/ reduction mechanisms (i.e. Cytochrome P450, Flavin Mono-Oxygenase), transferase reactions (i.e. Glutathione S-Transferase, Glycosyltransferases, Acetyltransferases), adduct formation, and repair mechanisms. Prerequisite: CHEM 315. Recommended BIOL 121

CHEM 359: Symmetry and  Spectroscopy (offered in even years)
Symmetry, group theory and molecular orbital theory will be used to explore and explain the behavior of chemical systems on the molecular and atomic scale.   The emphasis will be to develop orbital theory in order to gain an understanding of observed spectroscopic behavior such as Raman, IR and UV.  Additionally, symmetry and orbital theory will be used to explain chemical reactivity using models such as Woodward-Hoffman rules and photochemical selection rules.   Prerequisite: CHEM 318

So students can make long term plans, the department hopes to offer the following set of 2 credit, upper division courses in the academic years shown:

Even Academic Years (AY ending in Spring  14, 16, 18, ...)

  • Chemical Biology (APPROVED)
  • Climate and Habitat Change (APPROVED)
  • Environmental Chemistry B: Soil and Water
  • Industrial and Engineering Processes (APPROVED)
  • Nanomaterials (APPROVED)
  • Molecular Design (Organic) (APPROVED)
  • Xenobiotic Metabolism (APPROVED)
  • Analysis of Biomaterials (APPROVED)
  • Biomacromolecules
  • Symmetry and Spectroscopy (APPROVED)
  • Signal Transduction/Neurochemistry

Odd Academic Years (AY ending in Spring 15, 17, 19, ...)

  • Chemical Biology (APPROVED)
  • Climate and Habitat Change (APPROVED)
  • Environmental Chemistry A: Atmosphere
  • Industrial and Engineering Processes (APPROVED)
  • Polymers
  • Molecular Design (Inorganic)
  • Sustainable Energy 
  • Medicinal Chemistry
  • Electronics and Instrumental Design
  • Structure Elucidation
  • Separation Science
  • Insights into Mechanisms